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CBD Could Be the Fastest Acting Anti-Depressant Available

Are you one of the 18 percent of adults who suffers from a mental health condition? Or maybe one of the 8.1% of Americans age 20 or over who have suffered from depression at some point – or worse on-going with no relief from current pharmacueticals options?

Millions of people live with feelings of overwhelming depression day in and day out with no sign of relief in sight – until now.

A study conducted by Raquel Ling, of the Universidad de Cantabria, and published in Neuropharmacology, has found that CBD – the non-psychoactive cannabinoid found in the cannabis plant – may provide the fast-acting relief for depression that patients have been hoping for.

“Our findings indicate that CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signaling through a 5-HT1A receptor-dependent mechanism,” researchers wrote.

To conduct the study neuroscientists performed surgery on some of the 40 mice in the study, removing a region of their brains called the olfactory bulb. By removing this part of their brain, they caused the mice symptoms including hyperactivity, memory impairment, and decreased interested in being rewarded with sugar – which can be effectively treated by the compounds used in human antidepressants.

These so-called OBX mice are practically a standard and are often used when researching anything related to the causes and potential treatments for depression.

During their research scientists found that the OBX mice, when compared to the mice who were given a placebo, showed significantly reduced symptoms of hyperactivity within 30 minutes of CBD being administered. In fact, daily administration of CBD was found to completely reverse the effects of the OBX surgery on the loss of interest in sugar symptom after only one week.

During examination of the chemical activity within the mice brains, researchers found that CBD caused an increased release of serotonin and glutamate. Both mice with and without the OBX surgery saw a dramatic increase in glutamate immediately after the initial dose of CBD, and continuously with repeated administration. Serotonin on the other hand, did not increase as dramatically and only continued to increase for mice with OBX surgery.

Many pharmaceutical medications that are available to those suffering from depression aim to boost serotonin and glutamate levels – but it can take weeks of consistent use before they become the least bit effective; not to mention the lengthy list of side effects, including potentially making your symptoms of depression worse or even causing thoughts of suicide.

Consider the potential dangers of prescription medications for depression it is no wonder that people are looking for safer and more natural alternatives. Luckily for anyone who needs relief sooner rather than later – and anyone who wants to try a natural treatment for depression – CBD may provide the fast-acting relief you have been waiting for.


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